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OCT tops angiography for spotting vascular changes in heart transplant patients

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Results showed 26 cases with evidence of abnormal intima (the innermost layer of an artery or vein) size, and 11 cases with severe intima thickening. Angiographic findings were normal in eight patients with severe thickening. Findings from OCT spurred medical management changes in 17 percent of cases. Those patients had normal angiographic findings.

“Intimal thickening is prevalent in this population and is often angiographically silent,” wrote Eimear McGovern “Our study demonstrated that, even in cases of severe intima thickening, angiography results were most often normal. OCT is readily able to identify structural coronary changes that have not become manifest in the form of lumen narrowing.”

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